ARSENAL
RULED OUT: Kieran Tierney (knee), Thomas Partey (thigh), Takehiro Tomiyasu (calf)
MIGHT PLAY: Alexandre Lacazette (personal reasons)
“Obviously there are private reasons that I cannot comment on. We will see if he’s available. There’s a good possibility that that’s the case.” – Mikel Arteta on Alexandre Lacazette
BRENTFORD
RULED OUT: Frank Onyeka (ankle)
AVAILABLE: Josh Dasilva (hamstring), Pontus Jansson (illness)
“Dasilva will be involved in the squad which is very positive; I am very pleased for him. My take on it would be a fit Josh would have been one of our best performing players this season.” – Thomas Frank
BRIGHTON AND HOVE ALBION
RULED OUT: Steven Alzate (illness), Shane Duffy (thigh), Jakub Moder (knee)
BURNLEY
RULED OUT: Johann Berg Gudmundsson (calf)
MIGHT PLAY: Ben Mee (knee), Erik Pieters (knee)
CHELSEA
RULED OUT: Callum Hudson-Odoi (back), Ben Chilwell (knee)
AVAILABLE: Romelu Lukaku (Achilles)
“Except for Ben Chilwell and Callum Hudson-Odoi, everybody seems to be OK. Romelu [Lukaku] was back in training yesterday, let’s see if he has any reaction or not.” – Thomas Tuchel
CRYSTAL PALACE
RULED OUT: Nathan Ferguson (hamstring)
MIGHT PLAY: Tyrick Mitchell (calf), Michael Olise (foot), Will Hughes (knock)
“Tyrick (Mitchell) and Michael (Olise) have had some individual training and a little more today. We have to wait until tomorrow, but they’ll only get involved if they’re 100 per cent fit.” – Patrick Vieira
EVERTON
RULED OUT: Andros Townsend (knee), Nathan Patterson (ankle)
MIGHT PLAY: Yerry Mina (thigh), Donny van de Beek (thigh)
LEICESTER CITY
RULED OUT: Jamie Vardy (knee), Wilfred Ndidi (knee), Ryan Bertrand (knee), Danny Ward (knee)
MIGHT PLAY: Boubakary Soumare (abductor muscle)
LIVERPOOL
MIGHT PLAY: Diogo Jota (knock)
“Diogo [Jota] got a knock that’s blown up slightly. A good chance that he will be alright but we need to have a closer look tomorrow. That’s it.” – Jurgen Klopp
MANCHESTER CITY
MIGHT PLAY: Kevin De Bruyne (cut), Kyle Walker (ankle), Cole Palmer (foot)
AVAILABLE: Ruben Dias (hamstring)
“They didn’t train today. Apparently, it will be so close after what happened on Wednesday but we will see. Kyle [Walker] had a big twist. He is getting better. We will see in the next hours, the next days. In football these kinds of things happen. We will adapt, adjust and go from here. Kevin [De Bruyne] had stitches after he had contact – it’s not a muscular injury.” – Pep Guardiola on Kyle Walker and Kevin De Bruyne
MANCHESTER UNITED
RULED OUT: Edinson Cavani (calf), Luke Shaw (leg), Raphael Varane (knock), Fred (hip), Scott McTominay (foot)
“Five players will still be missing for tomorrow and some of them probably also for the upcoming games. Fred, Scott [McTominay], Rafa Varane, Luke Shaw and Edinson Cavani – those are the five.” – Ralf Rangnick
NEWCASTLE UNITED
RULED OUT: Callum Wilson (calf), Kieran Trippier (foot)
MIGHT PLAY: Ryan Fraser (hamstring), Joe Willock (knee)
“I don’t think it’s too bad but was enough to bring him off against Wolves. We had a scan with him and it showed a very small problem so hopefully it wont be too long for him – we’ll see whether he makes this game. Joe [Willock] has made good progress. He’s trained this week so we hope to have him fit.” – Eddie Howe on Ryan Fraser and Joe Willock
NORWICH CITY
RULED OUT: Brandon Williams (unable to face parent club), Adam Idah (knee), Ozan Kabak (hamstring), Andrew Omobamidele (back), Josh Sargent (ankle)
AVAILABLE: Przemyslaw Placheta (ankle), Billy Gilmour (Covid)
“Płacheta is back from injury and training with us and Gilmour is back from his Covid issue. Andrew [Omobamidele] is waiting on a scan result in the next couple of weeks, but won’t be able to play again this season.” – Dean Smith
SOUTHAMPTON
MIGHT PLAY: Shane Long (ankle), Alex McCarthy (match fitness), Lyanco (match fitness)
AVAILABLE: Armando Broja
“We have to look at what the players offer. I have not decided yet, we have had some good sessions this week.” – Ralph Hasenhuttl on making big changes after last week’s 6-0 defeat
TOTTENHAM HOTSPUR
RULED OUT: Matt Doherty (knee), Japhet Tanganga (knee), Oliver Skipp (groin)
AVAILABLE: Ryan Sessegnon (thigh)
“The Doherty injury is really bad news, you know well the improvement in our team and it’s a pity to lose a player like him for the rest of the season. Also Tanganga and Skipp are not available, this bad news for us. Sessegnon is ready.” – Antonio Conte
WATFORD
RULED OUT: Cucho Hernandez (hamstring), Samuel Kalu (ankle), William Troost-Ekong (hamstring), Francisco Sierralta (calf)
WEST HAM UNITED
RULED OUT: Angelo Ogbonna (knee), Kurt Zouma (ankle)